Posted by: shrikantmantri | October 17, 2009

ABWGAT: Anchor Based Whole Genome Analysis Tool.

via Bioinformatics on 10/16/09


Publication Date: 2009 Oct 14 PMID: 19828577
Authors: Das, S. – Vishnoi, A. – Bhattacharya, A.
Journal: Bioinformatics

SUMMARY: Large numbers of genomes are being sequenced regularly and the rate will go up in future due to availability of new genome sequencing techniques. In order to understand genotype to phenotype relationships it is necessary to identify sequence variations at the genomic level. Alignment of a pair of genomes and parsing the alignment data is an accepted approach for identification of variations. Though there are a number of tools available for whole genome alignment none of these allows automatic parsing of the alignment and identification of different kinds of genomic variants with high degree of sensitivity. Here we present a simple web based interface for whole genome comparison named ABWGAT (Anchor Based Whole Genome Analysis Tool) that is simple to use. The output is a list of variations such as SNVs, INDELs, Repeat expansion and Inversion. AVAILABILITY: The web server is freely available to non-commercial users at the following address: http://abwgc.jnu.ac.in/~sarba/ CONTACT: dsarbashis@gmail.com SUPPLEMENTARY INFORMATION: Supplementary data are available at http://abwgc.jnu.ac.in/~sarba/cgi-bin/abwgc_retrival.cgi using job id 524, 526 and 528.

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